Mitochondrial networks of cumulus cells and oocyte quality

BACKGROUND: Mitochondria play vital roles in oocyte functions and they are critical indicators of quality which is important for fertilization development into viable offspring. Quality-compromised oocytes mitochondrial dysfunction plays a significant role correlated with infertility, developmental disorders embryo loss. A the cytoplasmic accumulation sufficient amount pool played by cumulus cells surrounding it.
 AIM: to conduct comparative analysis between state networks oocytes.
 MATERIALS AND METHODS: The study included 22 women aged 28 37 years inclusive (mean age 32.3 1.2 years) tubal infertility. During assisted reproductive technology procedures, 74 were obtained. 39 good their compared 35 bad respectively. After puncture ovarian follicles isolated stained fluorescent dye cell tracing imaging vivo. method confocal microscopy was used analyze three-dimensional organization mitochondria 2030 one follicular fluid. following parameters evaluate network: fluorescence decay time intensity.
 RESULTS: associated significantly higher (p = 0.032) than case identification negative signs.
 CONCLUSION: structure correlates (r 0.76) oocytes.